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| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Drug Information and Evidence-Based Medicine | 25% | - Drug Information Resources
|
| Topic 2: Patient-Centered Pharmacotherapy | 55% | - Monitoring and Follow-Up
|
| Topic 3: System-Based Standards and Population-Based Pharmacotherapy | 20% | - Medication-Use Systems
|
Question 1
A 25-year-old man with type 1 diabetes mellitus has recorded the following average blood - glucose concentrations for the past 5 days:
Which of the following changes in his insulin regimen is most appropriate?
A. Decrease the morning regular insulin.
B. Increase the evening NPH insulin.
C. Increase the evening regular insulin.
D. Increase the morning NPH insulin.
Question 2
A 68-year-old female patient is admitted to the ICU for acute decompensated heart failure. She is currently intubated due to acute respiratory failure and hypoxia. After intubation, her Richmond Agitation-Sedation Scale (RASS) score is +3, and her Confusion Assessment Method for the ICU (CAM-ICU) is positive for delirium. She denies pain.
Which of the following is the best recommendation for achieving her sedation goal of RASS equals zero?
A. Administer haloperidol 5 mg intravenously q4h as needed for delirium.
B. Initiate morphine 2 mg intravenously q6h as needed for delirium.
C. Administer lorazepam infusion at a rate of 1 mg/h.
D. Initiate propofol at 5 mcg/kg/min and titrate as needed.
Question 3
A 48 year old man attends a local pharmacy health fair for a blood pressure check. His blodd pressure on two recent occasions has averaged 138/88 mm Hg.
According to the American Society of Hypertension, what is this patient's blood pressure classification?
A. Prehypertension
B. Stage 2
C. Normotensive
D. Stage 1
Question 4
A pharmacotherapy specialist is interpreting a published paper describing a randomized controlled, double-bling study that was conducted to evaluate the effects of antihistamines on the failure rate of treatment of otitis media in children. In the study, 250 children received antihistamines and 264 did not. All children received appropriate antibiotic therapy. Treatment failures occurred in four (1.6%) of the children who received antihistamines and in 13 (4.9%) of those who did not. The difference is statistically significant (p<0.05, chi-square). Which of the following statements about these result is appropriate?
A. Knowledge of the rate and severity of adverse event in the study is needed to allow a therapeutic decision.
B. The sample size is inadequate to allow clinical conclusions.
C. Chi-square is not the appropriate statistical test.
D. Antihistamines should be administered to all children with otitis media who meet study entry criteria.
Question 5
Prednisone 10 mg orally daily is prescribed for a 68-year-old 60-kg patient with acute temporal arteritis. The pharmacotherapy specialist would recommend which of the following?
A. Dose should be increased to 60 mg daily.
B. Dose should be increased to 20 mg daily.
C. Prednisone should be discontinued after 2 Weeks.
D. Dose should be decreased to 5 mg daily.
Solutions:
| Question 1 Answer: D | Question 2 Answer: D | Question 3 Answer: A | Question 4 Answer: C | Question 5 Answer: C |
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